Study Shows Higher Risk for Later Autism Diagnosis for Low-Birth-Weight Babies
Oct. 17, 2011 — Low-birth-weight babies may be five times more likely to be later diagnosed with autism than kids born at a normal weight, according to a new study.
Researchers state it’s the first study that followed kids over time to confirm the link between low birth weight and diagnosis of autism spectrum disorder (ASD) in a massive group of infants followed for 21 years.
The results showed 5% of low-birth-weight babies were eventually diagnosed with autism spectrum disorder compared with an autism rate of about 1% in normal-weight babies.
“We anticipated that there would be a higher rate among this premature group,” states researcher Jennifer Pinto-Martin, MPH, PhD, director of the Pennsylvania Center for Autism and Developmental Disabilities Research and Epidemiology. “We did not expect that it would be five times higher than the general population.”
Pinto-Martin states the results aren’t cause for alarm, but rather a call for vigilance. She states kids who are born at low birth weight should be monitored and screened early and often for autism so they can benefit from early diagnosis and treatment.
“We really can do a lot with a young child,” Pinto-Martin tells WebMD. “Their brain is highly malleable and really ready for intervention, and the older they get the harder it gets.”
Low Birth Weight and Autism Risk
Low birth weight and premature birth are known risk factors for mental and movement disabilities. But researchers state the relationship between these risk factors and autism is not well understood.
In this study, published in Pediatrics, researchers followed 623 kids born at low birth weight (about 1 pound to about 4.4 pounds) between 1984 and 1989 in New Jersey.
All of the kids were screened for autism spectrum disorder at age 16. This initial autism screening showed that 117 kids screened positive for ASD and 506 screened negative for the disorder.
Secondary diagnostic testing for autism was conducted at age 21 on 70 of the kids who screened positive and 119 of those who screened negative for autism.
Overall, the results showed that about 5% of the 623 low-birth-weight kids in the study had ASD, compared with about 1% found by the CDC in the general population.
Low Birth Weight and Developmental Disabilities
Pinto-Martin states the autism rate may be even higher among the low-birth-weight babies born today.
At the time the babies in the study were born in the mid-1980s, a 1-pound baby that survived was considered a “miracle baby.” Now babies weighing 1 pound are routinely kept alive through advances in neonatal care.
Experts state low-birth-weight babies may face a number of developmental and movement disabilities as they grow up, and autism may one of them.
“As our technology in the neonatal intensive care units is able to grant babies that are born earlier and earlier and smaller and smaller to survive, there may be other consequences of that,” states Alycia Halladay, PhD, director of research for environmental sciences at Autism Speaks, an autism advocacy and science group. “That is definitely something to consider, and something that deserves further study.”
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Submited at Tuesday, October 18th, 2011 at 12:00 pm on Uncategorized by admin
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