Research sheds light on workings of anti-cancer drug

(Northwestern University) The copper sequestering drug tetrathiomolybdate (TM) has been shown in studies to be effective in the treatment of Wilson disease, a disease caused by an overload of copper, and certain metastatic cancers. That much is known. Very little, however, is known about how the drug works at the molecular level. A new study led by Northwestern University researchers now has provided an invaluable clue: the three-dimensional structure of TM bound to copper-loaded metallochaperones.

source : www.eurekalert.org

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Submited at Thursday, November 26th, 2009 at 7:00 pm on Cancer and Oncology by ethan
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