Study Identifies How Tamoxifen Stimulates Uterine Cell Growth And Cancer

UCSF researchers have identified a new “feed-forward” pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth. The research is significant in helping determine why tamoxifen and other synthetic estrogens are linked to increased rates of endometriosis and uterine cancer, and identifies a pathway that could be targeted in drug therapies for those diseases, researchers say.

source : www.medicalnewstoday.com

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Submited at Saturday, July 4th, 2009 at 8:00 am on Endocrinology by Gillan
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